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Assessment of CWD prion shedding in deer saliva with occupancy modeling

flounder9

flounder9

Member
thought some here might find interest in this...kind regards, terry

Subject: Assessment of CWD prion shedding in deer saliva with occupancy modeling

Assessment of CWD prion shedding in deer saliva with occupancy modeling

Kristen A. Davenporta, Brittany A. Mosherb, Brian M. Brostc, Davin M. Hendersona, Nathaniel D. Denkersa, Amy V. Nallsa, Erin McNultya, Candace K. Mathiasona and Edward A. Hoovera# + Author Affiliations

Prion Research Center, Microbiology, Immunology and Pathology Department, Colorado State University, Fort Collins, COa Fish, Wildlife and Conservation Biology Department, Colorado State University, Fort Collins, COb Marine Mammal Laboratory, Alaska Fisheries Science Center, National Oceanic and Atmospheric Administration, Seattle, WAc ABSTRACT

Detection of prions is difficult due to the peculiarity of the pathogen, which is a misfolded form of a normal protein. The specificity and sensitivity of detection methods are imperfect in complex samples, including excreta. Here, we combined optimized prion amplification procedures with a statistical method that accounts for false positive and false negative errors to test deer saliva for chronic wasting disease (CWD) prions. This approach enabled us to discriminate shedding of prions in saliva and detection of prions in saliva -- a distinction crucial to understanding the role of prion shedding in disease transmission and for diagnosis. We found that assay sensitivity and specificity were indeed imperfect, and we were able to draw several conclusions pertinent to CWD biology from our analyses:

(1) shedding of prions in saliva increases with time post-inoculation, but is common throughout the pre-clinical phase of disease;

(2) shedding propensity is influenced neither by sex nor by prion protein genotype at codon 96; and

(3) the source of prion-containing inoculum used to infect deer affects the likelihood of prion shedding in saliva -- oral inoculation of deer with CWD(+) saliva resulted in 2.77 times the likelihood of prion shedding in saliva compared to inoculation with CWD(+) brain.

These results are pertinent to horizontal CWD transmission in wild cervids. Moreover, the approach described is applicable to other diagnostic assays with imperfect detection.

FOOTNOTES

↵#Address correspondence to Edward A. Hoover, edward.hoover@colostate.edu. Copyright © 2017 American Society for Microbiology. All Rights Reserved.


http://jcm.asm.org/content/early/2017/11/02/JCM.01243-17.abstract


SATURDAY, NOVEMBER 11, 2017

Assessment of CWD prion shedding in deer saliva with occupancy modeling

http://chronic-wasting-disease.blogspot.com/2017/11/assessment-of-cwd-prion-shedding-in.html
 
Something I thought of while spending endless hours in the tree. If the prions can remain in the soil for years and can be taken up by plants etc shouldn't we be concerned about the food we are eating? Corn, beans, garden vegetables and fruit?? Obviously there are more prions in an infected animal but it would seem to me that the prions could also be in the plants fruit? Any research gone into this?
With mandatory testing in zone 603 in MN they have found 7 positive deer in the first 2 days of gun season. This is not gonna be good. As we saw what the did last year. Unlimited tags for $2.50. A landowners season where rifles were allowed followed by a sharpshooters season where they hunted over bait and at night. There won't be any deer in this zone in the next few years.
I would think long and hard before placing any mineral or feeding deer. It simply isn't worth the risk at this point.
 
MN Hunter said:
Something I thought of while spending endless hours in the tree. If the prions can remain in the soil for years and can be taken up by plants etc shouldn't we be concerned about the food we are eating? Corn, beans, garden vegetables and fruit?? Obviously there are more prions in an infected animal but it would seem to me that the prions could also be in the plants fruit? Any research gone into this?
With mandatory testing in zone 603 in MN they have found 7 positive deer in the first 2 days of gun season. This is not gonna be good. As we saw what the did last year. Unlimited tags for $2.50. A landowners season where rifles were allowed followed by a sharpshooters season where they hunted over bait and at night. There won't be any deer in this zone in the next few years.
I would think long and hard before placing any mineral or feeding deer. It simply isn't worth the risk at this point.
Click to expand...


Using in vitro prion replication for high sensitive detection of prions and prionlike proteins and for understanding mechanisms of transmission.

Claudio Soto Mitchell Center for Alzheimer's diseases and related Brain disorders, Department of Neurology, University of Texas Medical School at Houston.

***Recently, we have been using PMCA to study the role of environmental prion contamination on the horizontal spreading of TSEs. These experiments have focused on the study of the interaction of prions with plants and environmentally relevant surfaces. Our results show that plants (both leaves and roots) bind tightly to prions present in brain extracts and excreta (urine and feces) and retain even small quantities of PrPSc for long periods of time. Strikingly, ingestion of prioncontaminated leaves and roots produced disease with a 100% attack rate and an incubation period not substantially longer than feeding animals directly with scrapie brain homogenate. Furthermore, plants can uptake prions from contaminated soil and transport them to different parts of the plant tissue (stem and leaves). Similarly, prions bind tightly to a variety of environmentally relevant surfaces, including stones, wood, metals, plastic, glass, cement, etc. Prion contaminated surfaces efficiently transmit prion disease when these materials were directly injected into the brain of animals and strikingly when the contaminated surfaces were just placed in the animal cage. These findings demonstrate that environmental materials can efficiently bind infectious prions and act as carriers of infectivity, suggesting that they may play an important role in the horizontal transmission of the disease.

========================

Since its invention 13 years ago, PMCA has helped to answer fundamental questions of prion propagation and has broad applications in research areas including the food industry, blood bank safety and human and veterinary disease diagnosis.

https://prion2015.files.wordpress.com/2015/05/programguide1.pdf

http://www.tandfonline.com/doi/pdf/10.4161/pri.28467

P.157: Uptake of prions into plants

Christopher Johnson1, Christina Carlson1, Matthew Keating1,2, Nicole Gibbs1, Haeyoon Chang1, Jamie Wiepz1, and Joel Pedersen1 1USGS National Wildlife Health Center; Madison, WI USA; 2University of Wisconsin - Madison; Madison, WI USA

Soil may preserve chronic wasting disease (CWD) and scrapie infectivity in the environment, making consumption or inhalation of soil particles a plausible mechanism whereby na€ıve animals can be exposed to prions. Plants are known to absorb a variety of substances from soil, including whole proteins, yet the potential for plants to take up abnormal prion protein (PrPTSE) and preserve prion infectivity is not known. In this study, we assessed PrPTSE uptake into roots using laser scanning confocal microscopy with fluorescently tagged PrPTSE and we used serial protein misfolding cyclic amplification (sPMCA) and detect and quantify PrPTSE levels in plant aerial tissues. Fluorescence was identified in the root hairs of the model plant Arabidopsis thaliana, as well as the crop plants alfalfa (Medicago sativa), barley (Hordeum vulgare) and tomato (Solanum lycopersicum) upon exposure to tagged PrPTSE but not a tagged control preparation. Using sPMCA, we found evidence of PrPTSE in aerial tissues of A. thaliana, alfalfa and maize (Zea mays) grown in hydroponic cultures in which only roots were exposed to PrPTSE. Levels of PrPTSE in plant aerial tissues ranged from approximately 4 £ 10 ¡10 to 1 £ 10 ¡9 g PrPTSE g ¡1 plant dry weight or 2 £ 105 to 7 £ 106 intracerebral ID50 units g ¡1 plant dry weight. Both stems and leaves of A. thaliana grown in culture media containing prions are infectious when intracerebrally-injected into mice. ***Our results suggest that prions can be taken up by plants and that contaminated plants may represent a previously unrecognized risk of human, domestic species and wildlife exposure to prions.

===========

***Our results suggest that prions can be taken up by plants and that contaminated plants may represent a previously unrecognized risk of human, domestic species and wildlife exposure to prions.***

SEE ;

Friday, May 15, 2015

Grass Plants Bind, Retain, Uptake, and Transport Infectious Prions

Report

http://transmissiblespongiformencep...5/05/grass-plants-bind-retain-uptake-and.html

Furthermore, an unpublished study had indicated low level absorption of PrP from soil by tomato plants although it should be noted that this study had not been repeated. Details of this work would be sent to the SEAC Secretary. Dr Matthews explained that most of the manure from animals challenged with high doses of BSE had already been composted and used for coppicing. Members agreed that the risks from disposal of residual manure from experimental animals would be much less than historic risks of on farm contamination from naturally infected animals at the height of the BSE epidemic. ...SNIP...END

http://www.seac.gov.uk/minutes/final91.pdf

https://web.archive.org/web/20070623223549/http://www.seac.gov.uk/minutes/final91.pdf

http://chronic-wasting-disease.blogspot.com/2013/09/uptake-of-prions-into-plants.html

http://chronic-wasting-disease.blogspot.com/2015/05/land-spreading-of-tse-prion-disease.html

In conclusion, the results in the current study indicate that removal of furniture that had been in contact with scrapie-infected animals should be recommended, particularly since cleaning and decontamination may not effectively remove scrapie infectivity (31), even though infectivity declines considerably if the pasture and the field furniture have not been in contact with scrapie-infected sheep for several months. As sPMCA failed to detect PrPSc in furniture that was subjected to weathering, even though exposure led to infection in sheep, this method may not always be reliable in predicting the risk of scrapie infection through environmental contamination. These results suggest that the VRQ/VRQ sheep model may be more sensitive than sPMCA for the detection of environmentally associated scrapie, and suggest that extremely low levels of scrapie contamination are able to cause infection in susceptible sheep genotypes.
Keywords: classical scrapie, prion, transmissible spongiform encephalopathy, sheep, field furniture, reservoir, serial protein misfolding cyclic amplification

http://journal.frontiersin.org/article/10.3389/fvets.2015.00032/full

Wednesday, December 16, 2015

*** Objects in contact with classical scrapie sheep act as a reservoir for scrapie transmission ***

http://scrapie-usa.blogspot.com/2015/12/objects-in-contact-with-classical.html

*** Infectious agent of sheep scrapie may persist in the environment for at least 16 years ***

Gudmundur Georgsson1, Sigurdur Sigurdarson2 and Paul Brown3

http://jgv.sgmjournals.org/content/87/12/3737.full

kind regards, terry
 
For all the time you spend in your putting this info out there.... Why don't you take advice from anyone? Make your information SIMPLE, to the point & in terms the general public can understand.
WHATEVER you're trying to say!!.... I don't care if folks disagree with it.... How about something like this....
"The Government is putting CWD out there to infect people and wipe out all of mankind by the year 2025. Here's the Evidence...... "LINK" ".

"Are any of you folks interested in joining PETA? It's really great and I'm paying for the next 5 memberships who reply here. You all with me or what?!?!?"

"You guys hunt deer and eat them, your genitals will fall off if you eat a deer that's infected with CWD... Here's the proof "LINK" ".

"last night, darth vador came down from planet Vulcan and said, if i don't post about CWD, he'd melt my brain!" "Here's the video..... "

If you're gonna spend all this time on this, make this stuff make sense and boil this down to a concise point for folks. This is actually 2 cents to actually help you here! Whether I think this is insanity or not, irrelevant, just want you to make some sense and some honest tips if you are really trying to "make a difference" - whatever it is ;)
 
Sligh1 said:
Sligh1AdministratorStaff Member
For all the time you spend in your putting this info out there.... Why don't you take advice from anyone? Make your information SIMPLE, to the point & in terms the general public can understand.
WHATEVER you're trying to say!!.... I don't care if folks disagree with it.... How about something like this....

"The Government is putting CWD out there to infect people and wipe out all of mankind by the year 2025. Here's the Evidence...... "LINK" ".

"Are any of you folks interested in joining PETA? It's really great and I'm paying for the next 5 memberships who reply here. You all with me or what?!?!?"

"You guys hunt deer and eat them, your genitals will fall off if you eat a deer that's infected with CWD... Here's the proof "LINK" ".

"last night, darth vador came down from planet Vulcan and said, if i don't post about CWD, he'd melt my brain!" "Here's the video..... "

If you're gonna spend all this time on this, make this stuff make sense and boil this down to a concise point for folks. This is actually 2 cents to actually help you here! Whether I think this is insanity or not, irrelevant, just want you to make some sense and some honest tips if you are really trying to "make a difference" - whatever it is ;)
Click to expand...


Sligh1 if i thought 'you were helping me out here', i might take your post seriously. but by making fun of me, or cwd tse prion, and the severity there from, will not make it go away, it only helps negate a very bad situation, and i can't make it much simpler to read than the most updated peer review studies themselves. if you don't like what is posted, i can only suggest you don't read it, others are very interested, and should be. it's not going away, and your comments here Sir, are a very good example why. have a good day...

>How about something like this....

>"The Government is putting CWD out there to infect people and wipe out all of mankind by the year 2025. Here's the Evidence...... "LINK" ".

3. Prof. A. Robertson gave a brief account of BSE. The US approach was to accord it a very low profile indeed. Dr. A Thiermann showed the picture in the ''Independent'' with cattle being incinerated and thought this was a fanatical incident to be avoided in the US at all costs. ...

http://web.archive.org/web/20060307063531/http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf

Evidence That Transmissible Mink Encephalopathy Results from Feeding Infected Cattle Over the next 8-10 weeks, approximately 40% of all the adult mink on the farm died from TME. snip... The rancher was a ''dead stock'' feeder using mostly (>95%) downer or dead dairy cattle...

https://web.archive.org/web/20060614143939/http://www.bseinquiry.gov.uk:80/files/mb/m09/tab05.pdf

https://web.archive.org/web/20041028104003/http://www.bseinquiry.gov.uk:80/files/mb/m09a/tab01.pdf

https://web.archive.org/web/2004102...quiry.gov.uk:80/files/yb/1987/06/10004001.pdf

The occurrence of CWD must be viewed against the contest of the locations in which it occurred. It was an incidental and unwelcome complication of the respective wildlife research programmes. Despite its subsequent recognition as a new disease of cervids, therefore justifying direct investigation, no specific research funding was forthcoming. The USDA veiwed it as a wildlife problem and consequently not their province! ...page 26.

https://web.archive.org/web/20060517075005/http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf

BSE INQUIRY

*** The association between venison eating and risk of CJD shows similar pattern, with regular venison eating associated with a 9 FOLD INCREASE IN RISK OF CJD (p = 0.04). ***

snip...see full report ;

https://web.archive.org/web/2017012...einquiry.gov.uk/files/yb/1994/08/00004001.pdf

you can see more evidence here ;

http://chronic-wasting-disease.blogspot.com/2016/05/zoonotic-potential-of-cwd-prions-update.html

Subject: ***CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat

Chronic Wasting Disease (CWD)

Prevention

If CWD could spread to people, it would most likely be through eating of infected deer and elk. In a 2006-2007 CDC survey of U.S. residents, nearly 20 percent of those surveyed said they had hunted deer or elk and more than two-thirds said they had eaten venison or elk meat. However, to date, no CWD infections have been reported in people.

Hunters must consider many factors when determining whether to eat meat from deer and elk harvested from areas with CWD, including the level of risk they are willing to accept. Hunters harvesting wild deer and elk from areas with reported CWD should check state wildlife and public health guidance to see whether testing of animals is recommended or required in a given state or region. In areas where CWD is known to be present, CDC recommends that hunters strongly consider having those animals tested before eating the meat.

snip...

Page last reviewed: August 17, 2017 Page last updated: August 17, 2017 Content source: Centers for Disease Control and Prevention National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) Division of High-Consequence Pathogens and Pathology (DHCPP)

https://www.cdc.gov/prions/cwd/prevention.html

TUESDAY, SEPTEMBER 12, 2017

CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat

http://chronic-wasting-disease.blogspot.com/2017/09/cdc-now-recommends-strongly-consider.html

COLORADO THE ORIGIN OF CHRONIC WASTING DISEASE CWD TSE PRION?

*** Spraker suggested an interesting explanation for the occurrence of CWD. The deer pens at the Foot Hills Campus were built some 30-40 years ago by a Dr. Bob Davis. At or abut that time, allegedly, some scrapie work was conducted at this site. When deer were introduced to the pens they occupied ground that had previously been occupied by sheep.

IN CONFIDENCE, REPORT OF AN UNCONVENTIONAL SLOW VIRUS DISEASE IN ANIMALS IN THE USA 1989

http://webarchive.nationalarchives....www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf

ALSO, one of the most, if not the most top TSE Prion God in Science today is Professor Adriano Aguzzi, and he recently commented on just this, on a cwd post on my facebook page August 20 at 1:44pm, quote;

''it pains me to no end to even comtemplate the possibility, but it seems entirely plausible that CWD originated from scientist-made spread of scrapie from sheep to deer in the colorado research facility. If true, a terrible burden for those involved.'' August 20 at 1:44pm ...end

MONDAY, SEPTEMBER 25, 2017

Colorado Chronic Wasting Disease CWD TSE Prion Mandatory Submission of test samples in some areas and zoonosis

http://chronic-wasting-disease.blogspot.com/2017/09/colorado-chronic-wasting-disease-cwd.html

>"Are any of you folks interested in joining PETA? It's really great and I'm paying for the next 5 memberships who reply here. You all with me or what?!?!?"

>"You guys hunt deer and eat them, your genitals will fall off if you eat a deer that's infected with CWD... Here's the proof "LINK" ".

>"last night, darth vador came down from planet Vulcan and said, if i don't post about CWD, he'd melt my brain!" "Here's the video..... "

https://histodb11.usz.ch/Images/videos/video-004/video-004.html

https://web.archive.org/web/2016032...einquiry.gov.uk/files/yb/1992/11/04001001.pdf

Commentary: Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

http://journals.plos.org/plosone/ar...notation/933cc83a-a384-45c3-b3b2-336882c30f9d

https://www.frontiersin.org/articles/10.3389/fnagi.2016.00005/full

1: J Neurol Neurosurg Psychiatry 1994 Jun;57(6):757-8

Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery.

Gibbs CJ Jr, Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC.

https://www.ncbi.nlm.nih.gov/pubmed/8006664?dopt=Abstract


Terry S. Singeltary Sr.
 
flounder9 said:
Sligh1 if i thought 'you were helping me out here', i might take your post seriously. but by making fun of me, or cwd tse prion, and the severity there from, will not make it go away, it only helps negate a very bad situation, and i can't make it much simpler to read than the most updated peer review studies themselves. if you don't like what is posted, i can only suggest you don't read it, others are very interested, and should be. it's not going away, and your comments here Sir, are a very good example why. have a good day...

>How about something like this....

>"The Government is putting CWD out there to infect people and wipe out all of mankind by the year 2025. Here's the Evidence...... "LINK" ".

3. Prof. A. Robertson gave a brief account of BSE. The US approach was to accord it a very low profile indeed. Dr. A Thiermann showed the picture in the ''Independent'' with cattle being incinerated and thought this was a fanatical incident to be avoided in the US at all costs. ...

http://web.archive.org/web/20060307063531/http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf

Evidence That Transmissible Mink Encephalopathy Results from Feeding Infected Cattle Over the next 8-10 weeks, approximately 40% of all the adult mink on the farm died from TME. snip... The rancher was a ''dead stock'' feeder using mostly (>95%) downer or dead dairy cattle...

https://web.archive.org/web/20060614143939/http://www.bseinquiry.gov.uk:80/files/mb/m09/tab05.pdf

https://web.archive.org/web/20041028104003/http://www.bseinquiry.gov.uk:80/files/mb/m09a/tab01.pdf

https://web.archive.org/web/2004102...quiry.gov.uk:80/files/yb/1987/06/10004001.pdf

The occurrence of CWD must be viewed against the contest of the locations in which it occurred. It was an incidental and unwelcome complication of the respective wildlife research programmes. Despite its subsequent recognition as a new disease of cervids, therefore justifying direct investigation, no specific research funding was forthcoming. The USDA veiwed it as a wildlife problem and consequently not their province! ...page 26.

https://web.archive.org/web/20060517075005/http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf

BSE INQUIRY

*** The association between venison eating and risk of CJD shows similar pattern, with regular venison eating associated with a 9 FOLD INCREASE IN RISK OF CJD (p = 0.04). ***

snip...see full report ;

https://web.archive.org/web/2017012...einquiry.gov.uk/files/yb/1994/08/00004001.pdf

you can see more evidence here ;

http://chronic-wasting-disease.blogspot.com/2016/05/zoonotic-potential-of-cwd-prions-update.html

Subject: ***CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat

Chronic Wasting Disease (CWD)

Prevention

If CWD could spread to people, it would most likely be through eating of infected deer and elk. In a 2006-2007 CDC survey of U.S. residents, nearly 20 percent of those surveyed said they had hunted deer or elk and more than two-thirds said they had eaten venison or elk meat. However, to date, no CWD infections have been reported in people.

Hunters must consider many factors when determining whether to eat meat from deer and elk harvested from areas with CWD, including the level of risk they are willing to accept. Hunters harvesting wild deer and elk from areas with reported CWD should check state wildlife and public health guidance to see whether testing of animals is recommended or required in a given state or region. In areas where CWD is known to be present, CDC recommends that hunters strongly consider having those animals tested before eating the meat.

snip...

Page last reviewed: August 17, 2017 Page last updated: August 17, 2017 Content source: Centers for Disease Control and Prevention National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) Division of High-Consequence Pathogens and Pathology (DHCPP)

https://www.cdc.gov/prions/cwd/prevention.html

TUESDAY, SEPTEMBER 12, 2017

CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat

http://chronic-wasting-disease.blogspot.com/2017/09/cdc-now-recommends-strongly-consider.html

COLORADO THE ORIGIN OF CHRONIC WASTING DISEASE CWD TSE PRION?

*** Spraker suggested an interesting explanation for the occurrence of CWD. The deer pens at the Foot Hills Campus were built some 30-40 years ago by a Dr. Bob Davis. At or abut that time, allegedly, some scrapie work was conducted at this site. When deer were introduced to the pens they occupied ground that had previously been occupied by sheep.

IN CONFIDENCE, REPORT OF AN UNCONVENTIONAL SLOW VIRUS DISEASE IN ANIMALS IN THE USA 1989

http://webarchive.nationalarchives....www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf

ALSO, one of the most, if not the most top TSE Prion God in Science today is Professor Adriano Aguzzi, and he recently commented on just this, on a cwd post on my facebook page August 20 at 1:44pm, quote;

''it pains me to no end to even comtemplate the possibility, but it seems entirely plausible that CWD originated from scientist-made spread of scrapie from sheep to deer in the colorado research facility. If true, a terrible burden for those involved.'' August 20 at 1:44pm ...end

MONDAY, SEPTEMBER 25, 2017

Colorado Chronic Wasting Disease CWD TSE Prion Mandatory Submission of test samples in some areas and zoonosis

http://chronic-wasting-disease.blogspot.com/2017/09/colorado-chronic-wasting-disease-cwd.html

>"Are any of you folks interested in joining PETA? It's really great and I'm paying for the next 5 memberships who reply here. You all with me or what?!?!?"

>"You guys hunt deer and eat them, your genitals will fall off if you eat a deer that's infected with CWD... Here's the proof "LINK" ".

>"last night, darth vador came down from planet Vulcan and said, if i don't post about CWD, he'd melt my brain!" "Here's the video..... "

https://histodb11.usz.ch/Images/videos/video-004/video-004.html

https://web.archive.org/web/2016032...einquiry.gov.uk/files/yb/1992/11/04001001.pdf

Commentary: Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

http://journals.plos.org/plosone/ar...notation/933cc83a-a384-45c3-b3b2-336882c30f9d

https://www.frontiersin.org/articles/10.3389/fnagi.2016.00005/full

1: J Neurol Neurosurg Psychiatry 1994 Jun;57(6):757-8

Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery.

Gibbs CJ Jr, Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC.

https://www.ncbi.nlm.nih.gov/pubmed/8006664?dopt=Abstract


Terry S. Singeltary Sr.
Click to expand...
Im having some fun with you- yes. But- I’m also giving sincere feedback. Honestly.
I’m dead serious- I really don’t understand what you are trying to: change, prove, make people aware of or movement to follow. Seriously!
So, aside from me goofing on u a little (innocent fun) - please - with all due respect..... how about a 3-4 sentence paragraph or small summary you write out that’s boiling Down your point and goal here????
 
  • Deleted by Wapsi Tree Rat
Show…
Give us some background Terry, why are you so invested in this, do you hunt, do you make a living from deer/sheep, do you make a living studying deer/sheep? “Many find this interesting “, who are the many and why are they so interested. Great spot right here for a do over for you. Start fresh man explain your angle and background but most importantly condense the info to brief non scientists lingo with lincs to the studies for the folks looking for that. Is there any deer hunting offered in the Bacliff area?
 
Flounder I agree with others that your post are way over our heads (especially mine). I can’t even begin to comprehend what you are saying or your links so I don’t even try anymore.
I respect your knowledge and I want you to keep posting here but please bring it down to my level then we can have good discussion on CWD.
 
IMG_2054.PNG So the lead scientist on TSE fears that cwd may have been created by man. Using scrapie from sheep? Awesome. Kudos to those people. But we haven't learned from that so we are trying to infect monkeys with cwd?
Here is a snapshot of what's going on in southern Minnesota where it was first detected November of 2016. Extra seasons were added, unlimited tags, and sharpshooters brought in. They shot the hell out the deer in these areas. Look at where the positives are being found this year. It's 'spreading'. The MN DNR claims they caught it early.
Are the liberal harvest regulations contributing to the advancement of CWD? The red dots indicate positives from 2016. The blue dots indicate positives from 2017. CWD is no joke but I fear more money needs to spent on research than blasting every deer in a CWD zone.
 
I had a response all typed up, nearly identical to what Sligh posted. Not the first time I engaged Terry in regards to these medical professional speak posts. In fact, I quit even reading them a long time ago. His posts are just beyond frustrating. Maybe I'm just ignorant, or illiterate, although I don't really think I am, but dang Terry, it's like he's just checking the box posting a bunch of crap to say hey I told you so. CWD isn't a laughing matter, and there's so much we don't realize, so I have a tough time saying this is completely pointless. I'm frustrated because I want to know more, but the way this is presented, just loses me after the nonsense medical speak sentence and a link.
 
Mike311 said:
Give us some background Terry, why are you so invested in this, do you hunt, do you make a living from deer/sheep, do you make a living studying deer/sheep? “Many find this interesting “, who are the many and why are they so interested. Great spot right here for a do over for you. Start fresh man explain your angle and background but most importantly condense the info to brief non scientists lingo with lincs to the studies for the folks looking for that. Is there any deer hunting offered in the Bacliff area?
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i don't mean to confuse. but if i just say this or that without the science to back it up, i get the tin foil cap nut case replies, then if i post the science that shows this or that, then i am over everybody's head or i am the anti this or that. simply fact, lost my mom to an extremely rare strain of sporadic cjd called the Heidenhain Variant of Creutzfeldt Jakob disease, then had officials just tell me it happens from nothing, that it's just in the UK, that it's a spontaneous event over here. that was December 17, 1997. at the time the Oprah trial and cactus cattle feeders were going at it on T.V. ...then after her death i just started digging up old documents from the BSE Inquiry in England. even made a brief submission that they seemed very interested about, about nutritional supplements for humans, and some nutritional supplements MY NEIGHBORS MOTHER had been taking, she also died from cjd exactly one year to the day before my mother did, both cases confirmed. these pills contained bovine brain, eyes, and a laundry list of SRMs, nothing more than what was being fed to those 300,000 cattle in the UK that died from mad cow disease the typical c-type BSE. seems the atypical L-type BASE BSE is more virulent along with the atypical H-type BSE. all of which have been documented in the USA now. i guess one can argue the Washington case or whether on not is was Canadian or USA LOL! since then we now know that indeed atypical BSE typical BSE, atypical scrapie and typical scrapie are linked to sporadic CJD, and what some of us have been saying for decades that CWD is causing sporadic CJD in humans. i am not anti hunt, anti meat, anti gun, i have hunted (can't now because of neck and back), i eat meat, and i am pro 2nd Amendment. i just hate stupid and greed, and the tse prion disease continues to be spread because of those two reasons. the usda inc and the oie is the cause of all this imo. cervid industry was a pawn in a huge game of political chicken. well the rooster has finally come home to roost after decades of denial and just plain stupid. the studies have been there all along, because of corporate greed and political wrangling, and good PR machine, we now have to deal with it. and when you lay claim i'm just another conspiracy theorist, think tobacco and asbestos and a very long incubating disease, cancer, and protect the industry at all cost mentality. how did that work for us. ...it is what it is now$$$

Thursday, November 16, 2017

Texas Natural Meats Recalls Beef Products Due To Possible Specified Risk Materials Contamination

http://specifiedriskmaterial.blogspot.com/2017/11/texas-natural-meats-recalls-beef.html

bottom line, i don't want to eat tse prions, and you should not either, they can kill you and yours and others...

i hoped that helped explain my situation...

kind regards, terry
 
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