I've been looking at both the 350 and 450. I wanted a tack driving stand gun back before these were legal and got the 20 ga savage 220 which I love, but hate the sabot availability (price hurts too, but don't shoot a lot). I know deer die with any gun when you hit them right, but its always nice to have some forgiveness as things don't always go as planned - from reports I've heard on the 350 has very small holes, limited knockdown, etc so that concerns me the most with that option. I like the low recoil and how it's quieter, which is good for upcoming kids I'll have to get out hunting in a couple years. The 450 I've heard you don't want to shoot it without hearing protection or you'll regret it, but great knockdown. Also heard it kicks like a 12 gauge, which I'm used to the recoil so not a huge deal. Wish there was something popular in between! I am by no means a gun guy, but pictures of the rounds don't look drastically different so surprises me there's so much more noise and recoil to the 450. Maybe I'm getting bad info too, can never rule that out anymore from the internet. I keep going back and forth which one I'd want to go with...