Any catfish over 4lbs or so I use this method. Clean like you usually would, and cut out all discolored meat, red lateral line, and the yellow fatty stuff in the belly. Dip the fillets in a pan of boiling water for about 20 seconds. Then pull back out, pat dry, bread, and then fry. Gets rid of a lot of the muddy fishy taste, and after doing it once and seeing the water after your done, you'll do it every time.